Time trend of UVB irradiation and the vitamin D concentration in German type 1 diabetes patients
J Langer, M Penna-Martinez, M Wallasch, D Bon… - The Journal of Steroid …, 2013 - Elsevier
BACKGROUND: Type 1 diabetes (T1D) is an autoimmune disease which is characterised by
the destruction of insulin-producing beta cells in human pancreas leading consequently to a
hyperglycaemic metabolism. Recent studies have shown that low cholecalciferol (25 (OH)
D3) concentrations may contribute to the development of T1D. The 25 (OH) D3 status
depends mostly on human skin production influenced by exposure to UVB radiation. Our
intention was to examine whether there was a change in UVB radiation in the past years and …
the destruction of insulin-producing beta cells in human pancreas leading consequently to a
hyperglycaemic metabolism. Recent studies have shown that low cholecalciferol (25 (OH)
D3) concentrations may contribute to the development of T1D. The 25 (OH) D3 status
depends mostly on human skin production influenced by exposure to UVB radiation. Our
intention was to examine whether there was a change in UVB radiation in the past years and …
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